Direct Mono-Iodination of Phthalic Anhydride

Abstract

This thesis had for its general purpose, then, the production of iodo-phthalic anhydride compounds by means of new and better methods. An extensive search of the literature was made as preliminary work on the subject, and several articles pertaining to the various iodophthalic anhydrides and acids were disclosed. Summaries of the significant ones follow. . . . Thus, after this preliminary literature research, the specific primary purpose and object of this thesis became the attempted preparation of either 3- or 4-iodo-phthalio anhydride by direct iodination of the anhydride ring, and, if successful, the secondary object was the condensation of the product with resorcinol to give a fluorescein containing an iodine in the acid residue. (Those fluoresceins mentioned above contain halogen atoms on the resorcinol residues.) [From Introduction]